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Intermittent compared to continuous real-time fMRI neurofeedback boosts control over amygdala activation

机译:与连续实时fmRI神经反馈相比,间歇性增强了对杏仁核活化的控制

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摘要

Real-time fMRI neurofeedback is a feasible tool to learn the volitional regulation of brain activity. So far, most studies provide continuous feedback information that is presented upon every volume acquisition. Although this maximizes the temporal resolution of feedback information, it may be accompanied by some disadvantages. Participants can be distracted from the regulation task due to (1) the intrinsic delay of the hemodynamic response and associated feedback and (2) limited cognitive resources available to simultaneously evaluate feedback information and stay engaged with the task. Here, we systematically investigate differences between groups presented with different variants of feedback (continuous vs. intermittent) and a control group receiving no feedback on their ability to regulate amygdala activity using positive memories and feelings. In contrast to the feedback groups, no learning effect was observed in the group without any feedback presentation. The group receiving intermittent feedback exhibited better amygdala regulation performance when compared with the group receiving continuous feedback. Behavioural measurements show that these effects were reflected in differences in task engagement. Overall, we not only demonstrate that the presentation of feedback is a prerequisite to learn volitional control of amygdala activity but also that intermittent feedback is superior to continuous feedback presentation.
机译:实时功能磁共振成像神经反馈是学习大脑活动的自愿调控的可行工具。到目前为止,大多数研究都提供连续的反馈信息,这些信息在每次批量采集时都会呈现出来。尽管这可以最大程度地提高反馈信息的时间分辨率,但可能会带来一些缺点。由于(1)血流动力学反应和相关反馈的内在延迟,以及(2)可用于同时评估反馈信息并保持参与任务的有限认知资源,参与者可能会分心。在这里,我们系统地研究了具有不同反馈形式(连续与间歇性)的组之间的差异,以及没有收到关于使用积极的记忆和感觉来调节杏仁核活动能力的反馈的对照组。与反馈组相比,在没有任何反馈呈现的组中没有观察到学习效果。与接受连续反馈的组相比,接受间歇反馈的组显示出更好的杏仁核调节性能。行为测量表明,这些影响反映在任务投入的差异中。总的来说,我们不仅证明反馈的呈现是学习对杏仁核活动进行自愿控制的先决条件,而且间歇性反馈优于连续反馈。

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